According to the book “Past and Present”, the building at 45 Court Street was the home of the Empire Drug Store, established in 1843 by R.C. Trivette. From 1855 to 1880, druggist D.J. H. Chubbuck did business under the Sign of the Golden Mortar at 45 Court Street. Among the occupants were also W.M. Quirk’s Poor Man’s Pharmacy and Webster’s Cut Rate Drugstore. Pharmacies continued on this site until Jacob Eisenberg’s drugstore closed in 1938.

Upstairs was an old bookbindery, originating about 1858 and owned by La Fayette Safford for many years. Beginning in 1939, the right half of the storefront was occupied by the National Peanut Company, then by Planter’s Peanut Company, followed by M&DR Nuts, the present occupant. The building appears to have been altered at street level, and the upper windows and cornice have been changed.

According to Broome County Historian Gerald Smith the building at 45 Court Street is one of the oldest in the City. “A lot of buildings in that area of downtown were built between 1838 and 1880.”